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Best Time To Take BCAAs: Branched-Chain Amino Acids

New to the gym, a competitive athlete, or weekend warrior? Learn how branched-chain amino acids (BCAAs) work and the best time to take them.

Table of Contents

By: Chris Lockwood, PhD, CSCS

Are you new to the gym, a competitive athlete, bodybuilder, CrossFitter, endurance enthusiast or weekend warrior?

If you fall into any of those categories, there’s a good chance you’ve supplemented with, or have considered using a branched-chain amino acid supplement (BCAA) - or post-workout - to improve your performance or promote faster recovery.

Best Time To Take BCAAs

The ideal time to take branched-chain amino acids is during workouts by adding 5-10 grams to your shake regimen, both pre-workout or post-workout, to fuel your body and repair your muscles.

When a high quality, high protein supplement isn’t on the menu, the amino acid benefits of BCAAs can help amplify the benefits of aminos to your muscles. Thus, the effect of BCAA powder supplements can mean greater muscle growth.

In other words, you can occasionally consume less protein and likely still reap the muscle-supporting benefits of an otherwise high-quality, high protein load. At the very least, you minimize the catabolic (muscle breakdown) effects of too much protein.

2:1:1 BCAA Ratio

While you can take a single amino acid supplement to get the benefits, by taking a 2:1:1 (leucine-to-isoleucine-to-valine) ratio you get more bang for your buck.

The all-star when it comes to aminos is the essential amino acid Leucine. An 'Essential' amino acid simply means the body cannot produce the amino naturally.

Additionally, researchers in one study found that 4.2 grams of the BCAA leucine, when added to a low-quality and low-protein (10 g) drink, significantly amplified the anabolic effects of weight training in both younger and older adults. [Atherton PJ et al. Clin Nutr 2016; S0261-5614(16)30071-1]

BCAA Amino Acids: A Natural Fatigue Fighter

If you’ve gorged on Thanksgiving turkey, you know the feeling of fatigue that sets in and makes you want to crawl into bed.

In addition to the extra protein, that all-American bird feast provides the cathartic benefits of a high-dose of the essential amino acid, tryptophan; the amino acid responsible for increasing the sleep-inducing hormone, serotonin.

However, that same tryptophan that makes family holidays bearable by putting you into Sleepy Town also increases within your brain as you exercise.

By blocking or delaying the uptake of tryptophan into the brain you can delay exercise fatigue and increase your total training volume.

Increasing training volume is the necessary variable for achieving your goals! Since this is an article about the best time to take BCAAs, it probably won’t surprise you that BCAAs directly compete with tryptophan for uptake into the brain.

In fact, in a recent systematic review, researchers concluded that supplementation with BCAA pre-workout supplements prior or during endurance exercise reduces fatigue, perceived effort, muscle damage, and pain sensation, increases the anabolic response to exercise, and improves recovery and the immune system response to exercise. [Salinas-Garcia ME et al. Nutr Hosp 2015;31:577-89.]


Just as you’re working diligently every single day to improve your health and fitness, we work alongside you, improving our products so that you can keep raising the bar.

We’ve tailored this new version of Alpha Amino to include a well-studied 2:1:1 BCAA ratio for optimal performance in addition to 11 essential amino acids. An integral part of the Alpha Amino BCAA formula is electrolytes, which help keep your body hydrated and ready to tackle any challenge


About Chris Lockwood

Dr. Lockwood is president of LOCKWOOD, LLC, an innovation, research, and consulting firm within the dietary supplement, nutrition and fitness industries. Beginning in Fall 2017, will also begin serving as an Adjunct Professor at Auburn University, School of Kinesiology. He has raised over $1.04MM in cash donations toward protein and dietary supplement research, is the lead inventor on five patents and pending applications, co-authored 58 peer-reviewed manuscripts and presentations, has authored 100s of consumer and trade articles, and is widely regarded as one of the foremost experts in sports nutrition and dietary supplements. He has previously served as Editor-in-Chief of Muscle & Fitness and M&F Hers magazines, Senior Category Director of the Diet, Energy, Food and Beverage category of GNC, Senior Brand Manager of ABB, and as Chief Scientific Officer of 4Life Research.


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